000030464 001__ 30464
000030464 005__ 20131002114015.0
000030464 0248_ $$aoai:doc.rero.ch:20121011152003-HQ$$punifr$$ppostprint$$prero_explore$$zcdu34$$zthesis_urn$$zreport$$zthesis$$zbook$$zcdu54$$zjournal$$zcdu16$$zpreprint$$zcdu1$$zdissertation
000030464 041__ $$aeng
000030464 080__ $$a54
000030464 100__ $$aGriffete, Nébéwia$$uAdolphe Merkle Institute and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland - Department of Physics and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland
000030464 245__ $$9eng$$aAmino covalent binding approach on iron oxide nanoparticle surface: toward biological applications
000030464 269__ $$c2012-09-26
000030464 520__ $$9eng$$aWe report on the synthesis and the surface modification of different types of magnetic iron oxide particles by developing an original process based on diazonium salts chemistry. Particles were first coated with amino groups and then subjected to polyethylene glycol (PEG) surface modification. They were subsequently characterized by Transmission electron microscopy, infrared spectroscopy, diffraction light scattering and by Zeta potential. To show the efficiency of this surface modification method, the potential cytotoxicity and (pro-)inflammatory effect of the PEG magnetic particles were also analyzed in vitro. This covalently surface modification approach based on diazonium salts chemistry provides individually dispersed, PEG-modified magnetic nanoparticles suitable for biological applications.
000030464 695__ $$9eng$$aIron oxide nanoparticles ; Surface modification ; Diazonium salts ; Biological applications
000030464 700__ $$aClift, Martin J.D.$$uAdolphe Merkle Institute and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland
000030464 700__ $$aLamouri, Aazdine$$uUniv. Paris Diderot, Sorbonne Paris Cite, ITODYS, Paris, France
000030464 700__ $$aDigigow, Reinaldo G.$$uAdolphe Merkle Institute and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland
000030464 700__ $$aMihut, Adriana M.$$uAdolphe Merkle Institute and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland
000030464 700__ $$aFink, Alke$$uAdolphe Merkle Institute and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland - Department of Chemistry and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland
000030464 700__ $$aRothen-Rutishauser, Barbara$$uAdolphe Merkle Institute and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland - Respiratory Medicine, Bern University Hospital, Inselspital, Switzerland
000030464 700__ $$aDietsch, Hervé$$uAdolphe Merkle Institute and Fribourg Center for Nanomaterials, University of Fribourg, Switzerland
000030464 773__ $$g2012///-$$tColloids and Surfaces A: Physicochemical and Engineering Aspects
000030464 775__ $$gPublished version$$ohttp://dx.doi.org/10.1016/j.colsurfa.2012.09.020
000030464 8564_ $$ffin_acb.pdf$$qapplication/pdf$$s675411$$uhttp://doc.rero.ch/record/30464/files/fin_acb.pdf$$yorder:1$$zpdf
000030464 918__ $$aFaculté des sciences$$bDécanat, Ch. du Musée 6A, 1700 Fribourg$$cChimie
000030464 919__ $$aUniversité de Fribourg$$bFribourg$$ddoc.support@rero.ch
000030464 980__ $$aPOSTPRINT$$bUNIFR$$fART_JOURNAL
000030464 990__ $$a20121011152003-HQ