Clinical Assessment of Potential Drug Interactions of Faldaprevir, a Hepatitis C Virus Protease Inhibitor, With Darunavir/Ritonavir, Efavirenz, and Tenofovir

Sabo, John P. ; Kort, Jens ; Ballow, Charles ; Haschke, Manuel ; Battegay, Manuel ; Fuhr, Rainard ; Girlich, Birgit ; Schobelock, Michael ; Feifel, Ulrich ; Lang, Benjamin ; Li, Yongmei ; Elgadi, Mabrouk

In: Clinical Infectious Diseases, 2014, vol. 59, no. 10, p. 1420-1428

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    Faldaprevir is a potent hepatitis C virus NS3/4A protease inhibitor. The findings from 3 phase 1 studies reported here suggest that faldaprevir can be safely coadministered with commonly used antiretrovirals