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Effect of Baseline Renal Function on Tenofovir-Containing Antiretroviral Therapy Outcomes in Zambia

Mulenga, Lloyd ; Musonda, Patrick ; Mwango, Albert ; Vinikoor, Michael J. ; Davies, Mary-Ann ; Mweemba, Aggrey ; Calmy, Alexandra ; Stringer, Jeffrey S. ; Keiser, Olivia ; Chi, Benjamin H. ; Wandeler, Gilles

In: Clinical Infectious Diseases, 2014, vol. 58, no. 10, p. 1473-1480

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    Title
    • Effect of Baseline Renal Function on Tenofovir-Containing Antiretroviral Therapy Outcomes in Zambia
    Author
    • Mulenga, Lloyd. Centre for Infectious Disease Research in Zambia
    • Musonda, Patrick. Centre for Infectious Disease Research in Zambia
    • Mwango, Albert. Ministry of Health, Lusaka, Zambia
    • Vinikoor, Michael J.. Centre for Infectious Disease Research in Zambia
    • Davies, Mary-Ann. School of Public Health and Family Medicine, University of Cape Town, South Africa
    • Mweemba, Aggrey. University Teaching Hospital
    • Calmy, Alexandra. University Hospital Geneva, Geneva
    • Stringer, Jeffrey S.. Centre for Infectious Disease Research in Zambia
    • Keiser, Olivia. Institute of Social & Preventive Medicine, University of Bern
    • Chi, Benjamin H.. Centre for Infectious Disease Research in Zambia
    • Wandeler, Gilles. Institute of Social & Preventive Medicine, University of Bern
    Document Type
    • Postprint
    Language
    • English
    Published in
    • Clinical Infectious Diseases, 2014, vol. 58, no. 10, p. 1473-1480. Oxford University Press
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:302108
    Summary
    In this large cohort of human immunodeficiency virus-infected patients receiving first-line antiretroviral therapy in Zambia, individuals who started a tenofovir-containing regimen despite baseline renal dysfunction showed comparable mortality and renal function improvement to those not receiving tenofovir