Effect of Baseline Renal Function on Tenofovir-Containing Antiretroviral Therapy Outcomes in Zambia

Mulenga, Lloyd ; Musonda, Patrick ; Mwango, Albert ; Vinikoor, Michael J. ; Davies, Mary-Ann ; Mweemba, Aggrey ; Calmy, Alexandra ; Stringer, Jeffrey S. ; Keiser, Olivia ; Chi, Benjamin H. ; Wandeler, Gilles

In: Clinical Infectious Diseases, 2014, vol. 58, no. 10, p. 1473-1480

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    In this large cohort of human immunodeficiency virus-infected patients receiving first-line antiretroviral therapy in Zambia, individuals who started a tenofovir-containing regimen despite baseline renal dysfunction showed comparable mortality and renal function improvement to those not receiving tenofovir