Acute Renal Failure on Immune Reconstitution in an HIV-Positive Patient with Miliary Tuberculosis

Jehle, Andreas W. ; Khanna, Nina ; Sigle, Jörg-Peter ; Glatz-Krieger, Katharina ; Battegay, Manuel ; Steiger, Jürg ; Dickenmann, Michael ; Hirsch, Hans H.

In: Clinical Infectious Diseases, 2004, vol. 38, no. 4, p. e32-e35

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    Summary
    Immune reconstitution syndrome following HAART in human immunodeficiency virus (HIV)-infected patients is characterized by inflammatory worsening of organ functions despite improvement in HIV surrogate markers of HIV infection. We describe a patient with miliary tuberculosis and urinary shedding of acid fast bacilli who developed acute renal failure 8 weeks after initiation of antituberculosis therapy and 6 weeks after initiation of HAART. The diagnostic workup and further course of disease implicated immune reconstitution syndrome as the cause of acute renal failure