Impact of Combined Low-Level Mupirocin and Genotypic Chlorhexidine Resistance on Persistent Methicillin-Resistant Staphylococcus aureus Carriage After Decolonization Therapy: A Case-control Study

Lee, Andie S. ; Macedo-Vinas, Marina ; François, Patrice ; Renzi, Gesuele ; Schrenzel, Jacques ; Vernaz, Nathalie ; Pittet, Didier ; Harbarth, Stephan

In: Clinical Infectious Diseases, 2011, vol. 52, no. 12, p. 1422-1430

Add to personal list
    Summary
    The clinical significance of low-level mupirocin and genotypic chlorhexidine resistance remains unclear. This case-control study demonstrates that combined low-level mupirocin and genotypic chlorhexidine resistance significantly increases the risk of persistent MRSA carriage after decolonization therapy (OR 3.4, 95% CI 1.5-7.8)