Immunovirological Response to Triple Nucleotide Reverse-Transcriptase Inhibitors and Ritonavir-Boosted Protease Inhibitors in Treatment-Naive HIV-2-Infected Patients: The ACHIEV2E Collaboration Study Group

Benard, Antoine ; van Sighem, Ard ; Taieb, Audrey ; Valadas, Emilia ; Ruelle, Jean ; Soriano, Vicente ; Calmy, Alexandra ; Balotta, Claudia ; Damond, Florence ; Brun-Vezinet, Françoise ; Chene, Geneviève ; Matheron, Sophie

In: Clinical Infectious Diseases, 2011, vol. 52, no. 10, p. 1257-1266

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    This European inter-cohort collaboration shows poorer immunological and virological responses with triple NRTI compared to PI/r-containing cART in treatment-naïve HIV-2-infected patients, regardless of baseline CD4 cell count. PI/r-containing cART should be recommended as first-line antiretroviral regimens in HIV-2 infection