Fulltext

Pooling European all-cause mortality: methodology and findings for the seasons 2008/2009 to 2010/2011

NIELSEN, J. ; MAZICK, A. ; ANDREWS, N. ; DETSIS, M. ; FENECH, T. M. ; FLORES, V. M. ; FOULLIET, A. ; GERGONNE, B. ; GREEN, H. K. ; JUNKER, C. ; NUNES, B. ; O'DONNELL, J. ; OZA, A. ; PALDY, A. ; PEBODY, R. ; REYNOLDS, A. ; SIDEROGLOU, T. ; SNIJDERS, B. E. ; SIMON-SORIA, F. ; UPHOFF, H. ; VAN ASTEN, L. ; VIRTANEN, M. J. ; WUILLAUME, F. ; MØLBAK, K.

In: Epidemiology and Infection, 2013, vol. 141, no. 9, p. 1996-2010

Add to personal list
    Title
    • Pooling European all-cause mortality: methodology and findings for the seasons 2008/2009 to 2010/2011
    Author
    • NIELSEN, J.. Department of Infectious Disease Epidemiology, Statens Serum Institut, Copenhagen, Denmark
    • MAZICK, A.. Department of Infectious Disease Epidemiology, Statens Serum Institut, Copenhagen, Denmark
    • ANDREWS, N.. Health Protection Agency, Health Protection Services, London, UK
    • DETSIS, M.. Department of Epidemiology, Hellenic Centre for Disease Control and Prevention, Athens, Greece
    • FENECH, T. M.. Infectious Disease Prevention and Control Unit, Valletta, Malta
    • FLORES, V. M.. Instituto de Salud Carlos III, Centro National de Epidemiologia, Madrid, Spain
    • FOULLIET, A.. Institut de Veille Sanitaire, Paris, France
    • GERGONNE, B.. National Board of Health and Welfare, Stockholm, Sweden
    • GREEN, H. K.. Health Protection Agency, Health Protection Services, London, UK
    • JUNKER, C.. Federal Statistical Office, Section of Population Health, Neuchatel, Switzerland
    • NUNES, B.. Departamento de Epidemiologia, Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisboa, Portugal
    • O'DONNELL, J.. Health Protection Surveillance Centre, Dublin, Ireland
    • OZA, A.. Health Protection Surveillance Centre, Dublin, Ireland
    • PALDY, A.. National Institute of Environmental Health, Budapest, Hungary
    • PEBODY, R.. Health Protection Agency, Immunisation Department, London, UK
    • REYNOLDS, A.. National Health Services, Edinburgh, Scotland, UK
    • SIDEROGLOU, T.. Department of Epidemiological Surveillance, Hellenic Centre for Diseases Control and Prevention, Vari, Attica, Greece
    • SNIJDERS, B. E.. National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, The Netherlands
    • SIMON-SORIA, F.. Instituto de Salud Carlos III, Centro National de Epidemiologia, Madrid, Spain
    • UPHOFF, H.. Hesse State Health Office, Department for Health Protection (HLPUG), Dillenburg, Germany
    • VAN ASTEN, L.. National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, The Netherlands
    • VIRTANEN, M. J.. National Institute for Health and Welfare, Epidemiologic Surveillance and Response Unit, Helsinki, Finland
    • WUILLAUME, F.. Public Health and Surveillance, Scientific Institute of Public Health, Luxemburg
    • MØLBAK, K.. Department of Infectious Disease Epidemiology, Statens Serum Institut, Copenhagen, Denmark
    Document Type
    • Postprint
    Language
    • English
    Published in
    • Epidemiology and Infection, 2013, vol. 141, no. 9, p. 1996-2010. Cambridge University Press
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:296860
    Summary
    Several European countries have timely all-cause mortality monitoring. However, small changes in mortality may not give rise to signals at the national level. Pooling data across countries may overcome this, particularly if changes in mortality occur simultaneously. Additionally, pooling may increase the power of monitoring populations with small numbers of expected deaths, e.g. younger age groups or fertile women. Finally, pooled analyses may reveal patterns of diseases across Europe. We describe a pooled analysis of all-cause mortality across 16 European countries. Two approaches were explored. In the ‘summarized' approach, data across countries were summarized and analysed as one overall country. In the ‘stratified' approach, heterogeneities between countries were taken into account. Pooling using the ‘stratified' approach was the most appropriate as it reflects variations in mortality. Excess mortality was observed in all winter seasons albeit slightly higher in 2008/09 than 2009/10 and 2010/11. In the 2008/09 season, excess mortality was mainly in elderly adults. In 2009/10, when pandemic influenza A(H1N1) dominated, excess mortality was mainly in children. The 2010/11 season reflected a similar pattern, although increased mortality in children came later. These patterns were less clear in analyses based on data from individual countries. We have demonstrated that with stratified pooling we can combine local mortality monitoring systems and enhance monitoring of mortality across Europe