Fulltext

Clustering of HCV coinfections on HIV phylogeny indicates domestic and sexual transmission of HCV

Kouyos, Roger D. ; Rauch, Andri ; Böni, Jürg ; Yerly, Sabine ; Shah, Cyril ; Aubert, Vincent ; Klimkait, Thomas ; Kovari, Helen ; Calmy, Alexandra ; Cavassini, Matthias ; Battegay, Manuel ; Vernazza, Pietro L. ; Bernasconi, Enos ; Ledergerber, Bruno ; Günthard, Huldrych F. ; Aubert, V. ; Barth, J. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Bucher, H.C. ; Burton-Jeangros, C. ; Calmy, A. ; Cavassini, M. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Francioli, P. ; Furrer, H. ; Fux, C.A. ; Gorgievski, M. ; Günthard, H. ; Haerry, D. ; Hasse, B. ; Hirsch, H.H. ; Hirschel, B. ; Hösli, I. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Kind, C. ; Klimkait, T. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Metzner, K. ; Müller, N. ; Nadal, D. ; Pantaleo, G. ; Rauch, A. ; Regenass, S. ; Rickenbach, M. ; Rudin, C. ; Schmid, P. ; Schultze, D. ; Schöni-Affolter, F. ; Schüpbach, J. ; Speck, R. ; Taffe, P. ; Tarr, P. ; Telenti, A. ; Trkola, A. ; Vernazza, P. ; Weber, R. ; Yerly, S. ; Kouyos, Roger D. ; Rauch, Andri ; Böni, Jürg ; Yerly, Sabine ; Shah, Cyril ; Aubert, Vincent ; Klimkait, Thomas ; Kovari, Helen ; Calmy, Alexandra ; Cavassini, Matthias ; Battegay, Manuel ; Vernazza, Pietro L. ; Bernasconi, Enos ; Ledergerber, Bruno ; Günthard, Huldrych F.

In: International Journal of Epidemiology, 2014, vol. 43, no. 3, p. 887-896

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    Titre
    • Clustering of HCV coinfections on HIV phylogeny indicates domestic and sexual transmission of HCV
    Auteur
    • Kouyos, Roger D.. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Rauch, Andri. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Böni, Jürg. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Yerly, Sabine. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Shah, Cyril. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Aubert, Vincent. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Klimkait, Thomas. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Kovari, Helen. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Calmy, Alexandra. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Cavassini, Matthias. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Battegay, Manuel. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Vernazza, Pietro L.. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Bernasconi, Enos. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Ledergerber, Bruno. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Günthard, Huldrych F.. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, 3Institute of Medical Virology, University of Zurich, Zurich, Switzerland, 4Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, 5Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, 6Department Biomedicine, University of Basel, Basel, Switzerland, 7Division of Infectious Diseases, Geneva University Hospital, Geneva, 8Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, 9Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, 10Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and 11Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Aubert, V.
    • Barth, J.
    • Battegay, M.
    • Bernasconi, E.
    • Böni, J.
    • Bucher, H.C.
    • Burton-Jeangros, C.
    • Calmy, A.
    • Cavassini, M.
    • Egger, M.
    • Elzi, L.
    • Fehr, J.
    • Fellay, J.
    • Francioli, P.
    • Furrer, H.
    • Fux, C.A.
    • Gorgievski, M.
    • Günthard, H.
    • Haerry, D.
    • Hasse, B.
    • Hirsch, H.H.
    • Hirschel, B.
    • Hösli, I.
    • Kahlert, C.
    • Kaiser, L.
    • Keiser, O.
    • Kind, C.
    • Klimkait, T.
    • Kovari, H.
    • Ledergerber, B.
    • Martinetti, G.
    • Martinez de Tejada, B.
    • Metzner, K.
    • Müller, N.
    • Nadal, D.
    • Pantaleo, G.
    • Rauch, A.
    • Regenass, S.
    • Rickenbach, M.
    • Rudin, C.
    • Schmid, P.
    • Schultze, D.
    • Schöni-Affolter, F.
    • Schüpbach, J.
    • Speck, R.
    • Taffe, P.
    • Tarr, P.
    • Telenti, A.
    • Trkola, A.
    • Vernazza, P.
    • Weber, R.
    • Yerly, S.
    • Kouyos, Roger D.. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Rauch, Andri. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Böni, Jürg. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Yerly, Sabine. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Shah, Cyril. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Aubert, Vincent. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Klimkait, Thomas. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Kovari, Helen. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Calmy, Alexandra. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Cavassini, Matthias. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Battegay, Manuel. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Vernazza, Pietro L.. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Bernasconi, Enos. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Ledergerber, Bruno. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    • Günthard, Huldrych F.. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • International Journal of Epidemiology, 2014, vol. 43, no. 3, p. 887-896. Oxford University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:296115
    Summary
    Background: HCV coinfection remains a major cause of morbidity and mortality among HIV-infected individuals and its incidence has increased dramatically in HIV-infected men who have sex with men(MSM). Methods: Hepatitis C virus (HCV) coinfection in the Swiss HIV Cohort Study(SHCS) was studied by combining clinical data with HIV-1 pol-sequences from the SHCS Drug Resistance Database(DRDB). We inferred maximum-likelihood phylogenetic trees, determined Swiss HIV-transmission pairs as monophyletic patient pairs, and then considered the distribution of HCV on those pairs. Results: Among the 9748 patients in the SHCS-DRDB with known HCV status, 2768(28%) were HCV-positive. Focusing on subtype B(7644 patients), we identified 1555 potential HIV-1 transmission pairs. There, we found that, even after controlling for transmission group, calendar year, age and sex, the odds for an HCV coinfection were increased by an odds ratio (OR) of 3.2 [95% confidence interval (CI) 2.2, 4.7) if a patient clustered with another HCV-positive case. This strong association persisted if transmission groups of intravenous drug users (IDUs), MSMs and heterosexuals (HETs) were considered separately(in all cases OR >2). Finally we found that HCV incidence was increased by a hazard ratio of 2.1 (1.1, 3.8) for individuals paired with an HCV-positive partner. Conclusions: Patients whose HIV virus is closely related to the HIV virus of HIV/HCV-coinfected patients have a higher risk for carrying or acquiring HCV themselves. This indicates the occurrence of domestic and sexual HCV transmission and allows the identification of patients with a high HCV-infection risk