Cumulative Exposure to Cell-Free HIV in Breast Milk, Rather Than Feeding Pattern per se, Identifies Postnatally Infected Infants

Neveu, Dorine ; Viljoen, Johannes ; Bland, Ruth M. ; Nagot, Nicolas ; Danaviah, Siva ; Coutsoudis, Anna ; Rollins, Nigel Campbell ; Coovadia, Hoosen M. ; Van de Perre, Philippe ; Newell, Marie-Louise

In: Clinical Infectious Diseases, 2011, vol. 52, no. 6, p. 819-825

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    Summary
    In a nested case-control study, postnatal HIV infection was strongly associated with cumulative HIV RNA breastmilk exposure, even after allowing for maternal CD4 and plasma viral load; cases ingested approximately 15 times more HIV-1 RNA particles than controls