Cumulative Exposure to Cell-Free HIV in Breast Milk, Rather Than Feeding Pattern per se, Identifies Postnatally Infected Infants
Auteur
Neveu, Dorine. Département d'Information Médicale et Laboratoire de Bactériologie-Virologie, Université Montpellier 1, EA 4205 and CHU Montpellier, Montpellier, France
Viljoen, Johannes. Africa Centre for Health and Population Studies, University of KwaZulu-Natal, South Africa
Bland, Ruth M.. Africa Centre for Health and Population Studies, University of KwaZulu-Natal, South Africa
Nagot, Nicolas. Département d'Information Médicale et Laboratoire de Bactériologie-Virologie, Université Montpellier 1, EA 4205 and CHU Montpellier, Montpellier, France
Danaviah, Siva. Africa Centre for Health and Population Studies, University of KwaZulu-Natal, South Africa
Coutsoudis, Anna. Department of Paediatrics and Child Health, University of KwaZulu-Natal
Rollins, Nigel Campbell. Department of Paediatrics and Child Health, University of KwaZulu-Natal
Coovadia, Hoosen M.. Victor Daitz Professor of HIV/AIDS Research, University of KwaZulu-Natal, KwaZulu-Natal
Van de Perre, Philippe. Département d'Information Médicale et Laboratoire de Bactériologie-Virologie, Université Montpellier 1, EA 4205 and CHU Montpellier, Montpellier, France
Newell, Marie-Louise. Africa Centre for Health and Population Studies, University of KwaZulu-Natal, South Africa
Type de document
Postprint
Langue
Anglais
Publié dans
Clinical Infectious Diseases, 2011, vol. 52, no. 6, p. 819-825. Oxford University Press
In a nested case-control study, postnatal HIV infection was strongly associated with cumulative HIV RNA breastmilk exposure, even after allowing for maternal CD4 and plasma viral load; cases ingested approximately 15 times more HIV-1 RNA particles than controls