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Helicobacter pylori Colonization in Infants and Young Children is Not Necessarily Associated with Diarrhoea

Rahman, M. M. ; Mahalanabis, D. ; Sarker, S. A. ; Bardhan, P. K. ; Alvarez, J. O. ; Hildebrand, P. ; Beglinger, C. ; Gyr, Klaus

In: Journal of Tropical Pediatrics, 1998, vol. 44, no. 5, p. 283-287

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    Titre
    • Helicobacter pylori Colonization in Infants and Young Children is Not Necessarily Associated with Diarrhoea
    Auteur
    • Rahman, M. M.. Department of Medicine and Research, University Hospital Basel, Switzerland
    • Mahalanabis, D.. International Centre for Diarrhoeal Disease Research Bangladesh
    • Sarker, S. A.. International Centre for Diarrhoeal Disease Research Bangladesh
    • Bardhan, P. K.. International Centre for Diarrhoeal Disease Research Bangladesh
    • Alvarez, J. O.. Department of International Health, University of Alabama at Birmingham Alabama, USA
    • Hildebrand, P.. Department of Medicine and Research, University Hospital Basel, Switzerland
    • Beglinger, C.. Department of Medicine and Research, University Hospital Basel, Switzerland
    • Gyr, Klaus. Department of Medicine and Research, University Hospital Basel, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Journal of Tropical Pediatrics, 1998, vol. 44, no. 5, p. 283-287. Oxford University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:294251
    Summary
    A cohort of 151 infants and young children aged 1-23 months from a poor peri-urban community of Bangladesh was studied to determine the relationship between Helicobacter pylori colonization and morbidity due to diarrhoea. A 13C urea breath test was performed to detect the presence of H. pylori.Children were followed up at home every alternate day for 6 months and diarrhoeal morbidity datawere collected. Diarrhoeal morbidity was compared between H. pylori-positive and H. pylori-negative children. Sixty-eight (45 per cent) children were H. pylori positive and 83 (55 per cent) were H. pylori negative. During the first 1-month period following the breath test, three (4.4 per cent) H. pylori-positive and four (4.8 per cent) H. pylori-negative children had diarrhoea. Thirty-two (47 per cent) of the children in the positive group and 43 (52 per cent) in the negative group had one or more episodesof diarrhoea during the 6-month follow-up period. Median number of diarrhoeal episodes was 1.0(range 1.0-4.0) in the H. pylori-positive children and 2.0 (range 1.0-5.0) in the H. pylori-negativechildren (p = 0.19). No significant difference was observed in the cumulative days with diarrhoea.The results of this study suggest that H. pylori colonization is not associated with diarrhoealmorbidity in infants and young children