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Control of Ascaris infection by chemotherapy: which is the most cost-effective option?

Guyatt, H.L. ; Chan, M.S. ; Medley, G.F. ; Bundy, D.A.P.

In: Transactions of The Royal Society of Tropical Medicine and Hygiene, 1995, vol. 89, no. 1, p. 16-20

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    Titre
    • Control of Ascaris infection by chemotherapy: which is the most cost-effective option?
    Auteur
    • Guyatt, H.L.. Department of Public Health and Epidemiology, Swiss Tropical Institute, Socinstrasse 57, CH-4002 Basel, Switzerland
    • Chan, M.S.. Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS, UK
    • Medley, G.F.. Ecosystems Analysis and Management Group, Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK
    • Bundy, D.A.P.. Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS, UK
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Transactions of The Royal Society of Tropical Medicine and Hygiene, 1995, vol. 89, no. 1, p. 16-20. Royal Society of Tropical Medicine and Hygiene
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:293784
    Summary
    Cost-effectiveness analysis is used to predict the optimal design of mass chemotherapy strategies in controlling Ascaris lumbricoides infection. The question of who to treat, how many to treat, and how often to treat are addressed using a population dynamic model of helminth transmission that assesses effectiveness in terms of disease reduction, combined with cost data from an actual control programme. Child-targeted treatment can be more cost-effective than population treatment in reducing the number of disease cases. The model also implies that, in the circumstances described here, enhancing coverage is a more cost-effective approach than increasing frequency of treatment