Broad-Range 16S rRNA Gene Polymerase Chain Reaction for Diagnosis of Culture-Negative Bacterial Infections
Rampini, Silvana K. ; Bloemberg, Guido V. ; Keller, Peter M. ; Büchler, Andrea C. ; Dollenmaier, Günter ; Speck, Roberto F. ; Böttger, Erik C.
In: Clinical Infectious Diseases, 2011, vol. 53, no. 12, p. 1245-1251
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- This study defines the role of 16S ribosomal RNA (rRNA) gene polymerase chain reaction (PCR) for diagnosis of culture-negative bacterial infections. Our data show that 16S rRNA PCR is particularly valuable for identification of pathogens in patients pretreated with antibiotics