Back
pdf
Journal article

Neural response dynamics of spiking and local field potential activity depend on CRT monitor refresh rate in the tree shrew primary visual cortex

  • Veit, Julia Visual Cognition Laboratory, Department of Medicine, Fribourg, Switzerland - Fribourg Center For Cognition, Department of Medicine, University of Fribourg, Switzerland
  • Bhattacharyya, Anwesha Visual Cognition Laboratory, Department of Medicine, Fribourg, Switzerland - Fribourg Center For Cognition, Department of Medicine, University of Fribourg, Switzerland
  • Kretz, Robert Division of Anatomy, Department of Medicine, University of Fribourg, Switzerland
  • Rainer, Gregor Visual Cognition Laboratory, Department of Medicine, Fribourg, Switzerland - Fribourg Center For Cognition, Department of Medicine, University of Fribourg, Switzerland
Show more…
    2011
Published in:
  • Journal of Neurophysiology. - 2011, vol. 106, no. 5, p. 2303-2313
electrophysiology
response latency
spike timing
neural coding
English Entrainment of neural activity to luminance impulses during the refresh of cathode ray tube monitor displays has been observed in the primary visual cortex (V1) of humans and macaque monkeys. This entrainment is of interest because it tends to temporally align and thus synchronize neural responses at the millisecond timescale. Here we show that, in tree shrew V1, both spiking and local field potential activity are also entrained at cathode ray tube refresh rates of 120, 90, and 60 Hz, with weakest but still significant entrainment even at 120 Hz, and strongest entrainment occurring in cortical input layer IV. For both luminance increments (“white” stimuli) and decrements (“black” stimuli), refresh rate had a strong impact on the temporal dynamics of the neural response for subsequent luminance impulses. Whereas there was rapid, strong attenuation of spikes and local field potential to prolonged visual stimuli composed of luminance impulses presented at 120 Hz, attenuation was nearly absent at 60-Hz refresh rate. In addition, neural onset latencies were shortest at 120 Hz and substantially increased, by ∼15 ms, at 60 Hz. In terms of neural response amplitude, black responses dominated white responses at all three refresh rates. However, black/white differences were much larger at 60 Hz than at higher refresh rates, suggesting a mechanism that is sensitive to stimulus timing. Taken together, our findings reveal many similarities between V1 of macaque and tree shrew, while underscoring a greater temporal sensitivity of the tree shrew visual system.
Faculty
Faculté des sciences et de médecine
Department
Département de Médecine
Language
  • English
Classification
Biological sciences
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/302460
Statistics
Document views: 28 File downloads:
  • rai_nrd.pdf: 53