Faculté des sciences

Mitochondrial genomic dysfunction causes dephosphorylation of SCH9 in the yeast Saccharomyces cerevisiae

Kawai, Shigeyuki ; Urban, Jörg ; Piccolis, Manuele ; Panchaud, Nicolas ; De Virgilio, Claudio ; Loewith, Robbie

In: Eukaryotic Cell, 2011, vol. 10, no. 10, p. 1367-1369

TORC1-dependent phosphorylation of Saccharomyces cerevisiae Sch9 was dramatically reduced upon exposure to a protonophore or in respiration-incompetent ρ⁰ cells but not in respiration-incompetent pet mutants, providing important insight into the molecular mechanisms governing interorganellar signaling in general and retrograde signaling in particular Plus

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    Summary
    TORC1-dependent phosphorylation of Saccharomyces cerevisiae Sch9 was dramatically reduced upon exposure to a protonophore or in respiration-incompetent ρ⁰ cells but not in respiration-incompetent pet mutants, providing important insight into the molecular mechanisms governing interorganellar signaling in general and retrograde signaling in particular