Laser speckle analysis synchronised with cardiac cycle
- Zakharov, Pavel Physics Department, University of Fribourg, Switzerland
- Scheffold, Frank Physics Department, University of Fribourg, Switzerland
- Weber, Bruno Univ. of Zurich (Switzerland)
-
2015
Published in:
- Proceedings SPIE. - 2015, vol. 9540, p. 954008–954008–9
Lasers
Speckle analysis
Blood flow
Brain activation
Cerebral blood flow
Laser speckle imaging
Tissues
English
We present an improved Laser speckle imaging approach to investigate the cerebral blood flow response following function stimulation of a single vibrissa. By synchronising speckle analysis with the cardiac cycle we are able to obtain robust averaging of the correlation signals while at the same time removing the contributions due to the pulsation of blood flow and associated tissue adaptation. With our inter-pulse correlation analysis we can follow second-scale dynamics of the cortical vascular system in response to functional brain activation. We find evidence for two temporally separated processes in the blood flow pattern following stimulation we tentatively attribute to vasodilation and vasoconstriction phases, respectively
- Faculty
- Faculté des sciences et de médecine
- Department
- Département de Physique
- Language
-
- English
- Classification
- Physics
- License
- License undefined
- Identifiers
-
- RERO DOC 257362
- DOI 10.1117/12.2185093
- Persistent URL
- https://folia.unifr.ch/unifr/documents/304499
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