Faculté des sciences

Principles of targeted mutagenesis in the moss Physcomitrella patens

Schaefer, Didier G. ; Zrÿd, Jean-Pierre

In: New Frontiers in Bryology:Physiology, Molecular Biology & Applied Genomics, 2004, vol. 4, p. 37-49

Highly efficient gene targeting is a unique feature of the moss Physcomitrella patens. It is now possible, in a multicellular eukaryote, to use the gene replacement technology which has been so successful in yeast. Careful design of transforming vector is nevertheless a key to successful generation of specific mutations. Plus

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    Summary
    Highly efficient gene targeting is a unique feature of the moss Physcomitrella patens. It is now possible, in a multicellular eukaryote, to use the gene replacement technology which has been so successful in yeast. Careful design of transforming vector is nevertheless a key to successful generation of specific mutations.