Faculté des sciences

Induction of host resistance to Rhipicephalus appendiculatus in rabbits: Effects of immunizing with detergent-solubilized tick tissue proteins

Dhadialla, T. S. ; Rutti, Bernard ; Brossard, Michel

In: Parasitology Research, 1990, vol. 76, no. 6, p. 536-539

Resistance to the hard tick, Rhipicephalus appendiculatus, was induced in rabbits by immunizing them with tick tissue proteins extracted with a detergent, Triton X-100. There was 25% mortality in female ticks fed on immunized rabbits as compared with those fed on controls. Similarly, there was a 40% and 60% reduction in the engorged weight and the weight of egg batches, respectively, of... Plus

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    Summary
    Resistance to the hard tick, Rhipicephalus appendiculatus, was induced in rabbits by immunizing them with tick tissue proteins extracted with a detergent, Triton X-100. There was 25% mortality in female ticks fed on immunized rabbits as compared with those fed on controls. Similarly, there was a 40% and 60% reduction in the engorged weight and the weight of egg batches, respectively, of ticks fed on immunized rabbits. Western blot analysis of detergent-solubilized tick tissue Western blot analysis of detergent-solubilized tick tissue proteins, carried out using immune sera, recognized a complex pattern of proteins. A strong reaction was observed with proteins with apparent molecular weights of 94000 and 40000 daltons.